Monday, December 26, 2011

Treating Your Allergy Symptoms With Promethazine

!±8± Treating Your Allergy Symptoms With Promethazine

Promethazine is a generic name for a class of antihistamine drugs used to prevent motion sickness, nausea, or vomiting; and for sedation, and the treatment of itching related to allergies. It is in the latter that we're interested in here, treating allergy symptoms and reactions with Promethazine, such as: nasal congestion, itching nose, clear runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. Brand names of promethazine include Phenadoz, Phenergan, and Promethegan. The FDA has approved Promethazine in 1951.

Promethazine is a prescription drug in the USA, but is available OTC in the United Kingdom, Switzerland, and in many other countries. For the treatment of allergy induced symptoms and itches, tablets may be taken with or without food, once every 4 to 8 hours. Though be very careful about giving it to children, especially those below 2 years of age - Promethazine can cause severe breathing problems or even death. Doctor's instructions must be followed carefully when given to a child of any age. Always keep this medicine out of children's reach.

As an anti-allergic medication, Promethazine can also be used to treat hay fever, or better known as allergic rhinitis. To treat allergic reactions, it can be given either alone or in combination with an oral decongestant. All patients are recommended to have their blood pressure measured frequently. Moreover, during long-term therapy, blood cell counts, liver function studies, EKG, and EEG should be undertaken. These studies and examinations are to be taken at intervals according to risk profile of the patient.

Promethazine can produce side effects that impair your thinking or reactions. It's required that when under medication you should not be driving or do any hazardous work which takes a great deal of concentration and alertness. Also, do not take alcohol, which serves to enhance the side effects of Prometazine.

Typical side effects of Promethazine include blurred vision, confusion, fatigue, dizziness, drowsiness, and dry mouth. Serious side effects, in which the patient should contact their physician immediately include seizures, respiratory depression (most common in children under two years of age or people with compromised function of pulmonal region), and malignant neuroleptic syndrome.

Before taking Promethazine, make sure you convey to your physician if you have or have ever experienced urination problems, digestive obstruction, stomach ulcers, glaucoma, sleep apnea, bone marrow disorder, or seizure disorder. You should also notify your physician, before taking the drug, if you have any history of heart disease, high blood pressure, or liver disease.

If you have any of the above conditions, you may not be able to take Promethazine unless your doctor requires you to take adjusted dosage, or undergo special laboratory tests during treatment. In addition, this medication is harmful to an unborn baby, so if you are pregnant or plan to get pregnant, avoid this treatment, or consult further with your doctor.

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a promethazine overdose may include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.

Disclaimer: This article should not be substituted for medical advice. Please talk to a qualified professional for more information about Promethazine.


Treating Your Allergy Symptoms With Promethazine

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Thursday, December 15, 2011

Common Crohn's Disease Medications

!±8± Common Crohn's Disease Medications

Crohn's disease is an inflammatory disease that primarily affects the small and large intestine, but can be present in other parts of the digestive tract. The disease was named after an American gastroenterologist, Burrill Crohn, who was the first to describe the disease.

Crohn's disease usually affects people in their teens or twenties, but there are cases where patients are struck with the disease later in life. The symptoms and severity of the disease vary from person to person.

At present, there are no medications that can cure Crohn's disease. Most patients experience periods of relapse followed by periods of remission that can last months or even years. During remissions the symptoms like abdominal pain, diarrhea and rectal bleeding are lessened. The improvements in symptoms are usually brought about by prescription medications or surgery. There are cases, where without treatment, the Crohn's goes into remission. No one knows why.

The goals of treatment are to bring about a remission, maintain it, minimize side effects from medications, and help to improve the overall quality of life of the patient. The medications for treating Crohn's disease include anti-inflammatory agents such as the 5ASA compounds, corticosteroids, topical antibiotics and immuno-modulators.

Crohn's Disease Medications

Crohn's disease medications include anti-inflammatory drugs that are intended to decrease intestinal inflammation; the way arthritis medications reduce joint inflammation. The different types of anti-inflammatory medications used to treat Crohn's disease are:

1. 5-ASA compounds such as sulfasalazine (Azulfidine) and mesalamine (Pentasa, Asacol, Dipentum, Colazal, Rowana enema, Canasa suppository) are used directly on the inflamed tissue.

Sulfasalazine is a prodrug that isn't active in its ingested form. It is usually broken down by bacteria in the colon to create two byproducts --5aminosalicylic acid (5-ASA) and sulfapyridine. No one is sure which of these byproducts is responsible for the activity of azulfidine. The 5-ASA is known for its therapeutic benefit, though it's not clear whether sulfapyridine offers any additional benefit.

5 aminosalicylic acid and sulfapyridine work as anti-inflammatory agents that treat the inflammation in the colon. The effectiveness is believed to be due to the local effect on the bowel, however there are also some beneficial systemic immune suppressant effects as well.

But like any medications 5-ASA is not without side effects. Some of the side effects are very frequent gastrointestinal disturbances. Nausea, vomiting, gastric distress and anorexia occur in about one out of every three patients. Likewise dizziness may also occur during but should be of little concern unless it becomes persistent.

There are also some less common side effects such as a drop in white blood cell counts or a type of anemia that happens more often in patients with arthritis. The chance of developing these side effects is about 6 out of every 10,000 patients. Some other rare, but possible side effects include fever, pale skin, sore throat, fatigue and unusual bleeding or bruising. If you experience any of these, you will likely be taken off the medication.

Additional side effects include headache, allergic reactions and photosensitivity. These side effects require medical attention since allergic reactions can cause difficulty swallowing, blistering, peeling, loosening of the skin, aching joints and muscles as well as unusual tiredness or weakness.

2. Corticosteroids act systematically without requiring direct contact with the inflamed tissue. These medications are used to decrease inflammation throughout the body. These drugs also have important, and dangerous side effects, if taken for long periods. You doctor can advise you best on this.

There are new classes of topical corticosteroids that are applied directly to the inflamed tissue. These new drugs have much fewer side effects compared to systematic corticosteroids.

3. Antibiotics such as metronidazole (Flagyl) and ciprofloxacin (Cipro). These medications decrease inflammation by unknown mechanisms.

Metronidazole is effective in killing anaerobic bacteria as well as certain parasites. Anaerobic bacteria is single a cell organism that lives in low oxygen environments, and causes disease in the abdomen, liver and pelvis. In terms of parasites, giardia lamblia and ameba are parasites that cause abdominal pain and severe diarrhea in most patients. The metronidazole blocks some of the cell functions of these parasites resulting in their demise.

Serious side effects of metronidazole are rare, but include seizures and damage to nerves that brings numbness as well as tingling in the extremities. If you have these side effects, contact your doctor at once, you'll need to stop taking this medication.

If you suspect you have Crohn's disease, you should first consult your primary care physician before taking other steps. Careful diagnosis and monitoring are the key to living comfortably with Crohn's.


Common Crohn's Disease Medications

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